How can rigorous clinical trials be conducted in contexts marked by insecurity, logistical constraints, and fragile health systems? This is the question addressed in the article published by Inserm on the OptiMA clinical trials, carried out in the Democratic Republic of the Congo (2017) and Niger (2021–2022).
Scientifically coordinated by Inserm, these trials were part of humanitarian projects led by ALIMA, aiming to improve the efficiency acute malnutrition management in children.
The article highlights the key role played by ALIMA teams in implementing this research in unstable contexts: ensuring the safety of activities, maintaining continuity of care, engaging with authorities and communities, and supporting families throughout the research protocol.
This feedback highlights the importance of designing research projects that are firmly rooted in operational realities, capable of generating robust data while also contributing to the strengthening of local health systems.
