Ebola
Ebola virus disease is a viral but often fatal hemorrhagic fever. Since its discovery in 1976, it has affected several countries in Central, West and East Africa, with major outbreaks, particularly in Guinea between 2013 and 2016.
ALIMA (The Alliance for International Medical Action) plays a key role in the fight against Ebola. In addition to treating patients, the NGO innovates in treatments, prevention, and vaccination to curb the spread of the virus and save lives.
What is Ebola virus disease?
Ebola virus disease (EVD) is an acute viral infection with an average fatality rate of 50% (ranging from 30% to 90% depending on the strain) (WHO). The virus belongs to the filovirus family and is transmitted through direct contact with the body fluids of an infected person or animal.
Origin and transmission of the Ebola virus
Where does the Ebola virus come from?
Named after a river in the Democratic Republic of Congo (DRC), where the first outbreaks occurred in 1976, Ebola has since triggered over 20 epidemics across Central and West Africa.
How is Ebola transmitted?
- Animal transmission: fruit bats are suspected of being the natural reservoir of the virus. Contact with infected animals (monkeys, antelopes, porcupines) can lead to human infection.
- Human-to-human transmission: the virus spreads via direct contact with an infected person’s body fluids (blood, sweat, urine, saliva, etc.). It can also be transmitted through unprotected sex or from mother to child through breastfeeding.
- Exposure of healthcare staff: without adequate protection, healthcare workers are particularly at risk.
Essential prevention measures
- Frequent handwashing
- Use of personal protective equipment (masks, gloves)
- Rapid isolation of infected patients
- Community awareness campaigns
- Vaccination
What are the symptoms of the Ebola virus?
Symptoms appear between 2 and 21 days after infection.
Early symptoms:
- High fever (+38°C)
- Extreme fatigue
- Headache and sore throat
Advanced symptoms:
- Vomiting and diarrhea
- Rashes
- Internal and external bleeding
Early diagnosis and rapid medical intervention significantly increase the chances of survival.
Take action
Support the fight against Ebola
Your support is crucial to saving lives and preventing future outbreaks.
Ebola treatments and vaccines
Recommended treatments
Since 2022, the WHO recommends two monoclonal antibody treatments proven to be effective against the Zaire strain of Ebola:
When administered early, these treatments increase the chances of recovery.
Vaccines against Ebola Zaire
- rVSV-ZEBOV: demonstrated 100% efficacy in a 2015 trial in Guinea.
- Ad26.ZEBOV and MVA-BN-Filo (Janssen): WHO-validated to strengthen protection.
Ongoing studies, such as PREVAC, led by ALIMA and its partners, continue to optimize vaccine strategies.
ALIMA's commitment in the fight against Ebola
Actions on the ground
Since 2014, ALIMA has been actively involved in the outbreaks in the DRC and Guinea:
- Establishment of Ebola Treatment Centers (ETCs)
- Diagnosis and patient care
- Community awareness campaigns
- Training of health workers
A major innovation: the CUBE
ALIMA has developed the Biosecure Emergency Room for Epidemics (CUBE), a care unit to isolate and treat patients while limiting risks for caregivers.
In 2019, Bill Gates awarded ALIMA the “Game-Changing Innovator” prize at the Reaching the Last Mile Forum in Abu Dhabi.
ALIMA, a key player in Ebola research
In collaboration with INSERM, the WHO, and other partners, ALIMA participates in several research programs aimed at:
- Improving treatments
- Optimizing vaccination strategies
- Reduce mortality rates
The PALM study, to which ALIMA contributed in the DRC, demonstrated that early treatment can lower mortality rates to below 10%.
On the ground
Related news

Lassa Fever Peak Hits Nigeria Again; ALIMA, in Partnership with the Ministry of Health and Communities in Owo, Southwest Nigeria, Combats the Disease
Lassa fever is an acute viral hemorrhagic fever endemic to west Africa, transmitted to humans by the Mastomys rat (natural reservoir for the virus), with

Surviving Cholera in Borno, North East Nigeria
As communities in Maiduguri recover from the recent flood that devastated the region rendering thousands homeless, ALIMA has stepped up door-to-door community sensitization on cholera

Mpox: DRC Mobilises for a Historic Vaccination Campaign
As the Mpox epidemic continues to spread in the Democratic Republic of Congo (DRC), hopes are turning to vaccination efforts. The DRC is set to